Scientist, In Vivo Pharmacology
Middlesex County, MA
Scientist, Rare Genetic Disease In-Vivo Pharmacology
Agios (agios.com) is a biopharmaceutical company committed to applying our scientific leadership in cellular metabolism to transform the lives of patients with cancer and rare genetic diseases. We are growing rapidly with an active research and discovery pipeline across both therapeutic areas. Agios has two approved oncology precision medicine and multiple first-in-class investigational therapies in clinical and/or preclinical development.
Agios is seeking a highly motivated individual for our rare genetic disease franchise who will be a lead individual supporting in vivo research activities across multiple programs for rare genetic diseases. Ideally, the successful candidate will tackle new areas of science that touch a variety of disciplines. The successful candidate will be expected to learn and explore new scientific domains and disease models. A high degree of learning agility and scientific acumen will be needed to succeed in this role.
This challenging career opportunity is within a fast-paced pharmacology group where this individual will be responsible for coordinating efforts across multiple functions to provide the optimal in vivo research and drug discovery program for our rare genetic disease franchise and programs
- Strategy for and oversight of mouse model development, in vivo deliverables and timelines
- Mouse model disease characterization
- Responsible for in-vivo target validation
- Perform in-vivo compound proof-of-concept studies
- Experience in managing studies remotely through CRO collaborators
- PhD with 2-4 years post graduate experience in one of the following areas of research: neuroscience, hematopoietic sciences or immunology.
- Experience designing and overseeing the generation of transgenic mouse models.
- Experience with small molecule pharmacokinetics and pharmacodynamics.
- Ability to work independently as well as to collaborate and influence in a cross-functional team setting.
- Excellent written and communication skills, strong sense of organization, record keeping, and time management.
- Committed to the safety and humane treatment of laboratory animals.
- A background in rare genetic diseases is desired.
- Experience in biomarker discovery in disease models is a plus