Principal Scientist - Cardiometabolic Disorders

Amgen Inc.

3.6

(9)

Thousand Oaks, CA

Why you should apply for a job to Amgen Inc.:

  • 67% say women are treated fairly and equally to men
  • 78% would recommend this company to other women
  • Ratings are based on anonymous reviews by Fairygodboss members.
  • Flexible work models that empower staff members to work where and when they are most productive
  • Award-winning PTO plan and bi-annual company-wide shutdowns
  • With 11 Employee Resource Groups, 60 chapters & 11000 members everyone has opportunity to connect, network & foster a culture of belonging
  • #R-173647

    Position summary

    potential for helping patients.

    We are seeking a dedicated and highly motivated Principal Scientist to become a member of the Department of Cardiometabolic Disorders within Amgen Research located in Thousand Oaks, CA. In this vital and exciting role you will be an ideator and drug hunter and are expected to identify therapeutic targets in cardiometabolic disease that are tractable and offer the opportunity of delivering disease-modifying potential in patients. The proposal and advancement of a drug discovery program will be based on a sound and compelling scientific rationale that may include validation from human genetics and/or clinical studies. Critical thinking, ingenuity, technical proficiency, excellent communication skills, integrity and the ability to work in a multi-disciplinary environment will be critical toward advancing programs in the cardiometabolic pipeline. You will initially work at the bench conducting in vivo and/or in vitro preclinical studies with a focus on PAH, vascular disease and/or heart failure. Over time, you will also demonstrate strong leadership skills and the ability to manage a team of scientists conducting drug discovery research.

    As part of the team, the candidate may also support other new and existing drug discovery programs in the department to help advance the best assets in the Cardiometabolic Disorders portfolio.
    Key responsibilities include:

    • Conceptualizing and proposing therapeutic targets for the treatment of cardiometabolic disease
    • Designing and performing in vitro and cell-based experiments
    • Independently performing data analysis and interpreting results
    • Communicating scientific results through written and oral presentations
    • Collaborating with teams from other functions in the company to advance our programs
    • Documenting work through written protocols, electronic laboratory notebooks and study reports.
    • Advising colleagues in areas of expertise

    Win

    What we expect of you

    We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a leader with these qualifications.
    Basic Qualifications:

    Doctorate degree and 3 years of scientific experience

    Or

    Master's degree and 4 years of scientific experience
    Or

    Bachelor's degree and 6 years of scientific experience
    Preferred Qualifications:

    • PhD with postdoctoral experience in cardiometabolic disease (industry experience is strongly preferred)
    • Strong target ideation capabilities and critical thinking to enable discovery of innovative medicines for patients
    • Exceptional in vivo and/or in vitro pharmacology skills and capability to independently design, implement and analyze studies with proper controls and generate reproducible high-quality data
    • Technical mastery of general molecular biology, biochemical, and cell-signaling techniques including immunoblotting, immunocytochemistry, RT-qPCR, immunoprecipitation, and ELISA
    • Basic knowledge of statistical methods applied in a consistent and rigorous manner to all data sets generated
    • Excellent written and oral communication skills and interpersonal skills that enable effective team interactions and communication of key data to all key stakeholders
    • A strong ability to collaborate cross-functionally in a multidisciplinary environment is critical
    • Capability to deliver high quality manuscripts, posters and presentations for internal and external peer-reviewed publication and conference attendance.
    • Understanding of human genetics and genomic data mining for target identification are a plus.

    Thrive

    What you can expect of us

    As we work to develop treatments that take care of others, we also work to care for our teammates' professional and personal growth and well-being.

    Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

    • Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
    • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
    • Stock-based long-term incentives
    • Award-winning time-off plans and bi-annual company-wide shutdowns
    • Flexible work models, including remote work arrangements, where possible

    Apply now

    for a career that defies imagination

    Objects in your future are closer than they appear. Join us.
    careers.amgen.com

    Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

    We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

    Salary Range
    136,258.00 USD - 157,146.00 USD

    Why you should apply for a job to Amgen Inc.:

  • 67% say women are treated fairly and equally to men
  • 78% would recommend this company to other women
  • Ratings are based on anonymous reviews by Fairygodboss members.
  • Flexible work models that empower staff members to work where and when they are most productive
  • Award-winning PTO plan and bi-annual company-wide shutdowns
  • With 11 Employee Resource Groups, 60 chapters & 11000 members everyone has opportunity to connect, network & foster a culture of belonging