Associate Director, Pharmacometrics

Janssen Research & Development, L.L.C., a Johnson & Johnson company, is looking for an Associate Scientific Director, Pharmacometrics to be located in Spring House PA, Chesterbrook PA, La Jolla CA,  Titusville NJ or Raritan NJ. Remote work options in the United States may be considered on a case-by-case basis and if approved by the Company.

At the Janssen Pharmaceutical Companies of Johnson & Johnson, we are working to create a world without disease. Transforming lives by finding new and better ways to prevent, intercept, treat and cure disease inspires us. We bring together the best minds and pursue the most promising science. We are Janssen. We collaborate with the world for the health of everyone in it. Learn more at www.janssen.com and follow us @JanssenGlobal.Janssen Research & Development, LLC is part of the Janssen Pharmaceutical Companies.

As the Associate Scientific Director, Pharmacometrics, you will conduct advanced PK/PD modeling research with emphasis on disease progression modeling and implementation of mechanism-based approaches. You will support product development as Pharmacometrics Leader by defining the dose-concentration-pharmacological effect relationships of drugs using modeling and simulation methodologies from data acquired at various stages of drug research and development.

THE SUCCESSFUL CANDIDATE WILL ALSO:

• Perform basic and clinical disease research, with a focus on Immunology, Oncology/Hematology, and/or Cardiovascular/Metabolic Disease compounds (small molecules, biologics, and other novel modalities such as gene-therapy).
• Perform population PK and PK/PD analysis for key dose/regimen selections and regulatory submissions.
• Use state-of-the-art computer modeling and simulation techniques to formulate various clinical trial design scenarios and outcome analyses.
• Actively maintain relationships and collaborate with colleagues within or outside the Clinical Pharmacology and Pharmacometrics organization and J&J at large
• Establish and Maintain external collaborations with Academic groups active in a variety of therapeutic areas worldwide.
• Serve as senior technical expert for the Pharmacometrics organization in the application of advanced PK/PD and disease modeling principles, as well as in mechanism-based concepts and processes.