Cell Therapy RnD Automation CoOp

Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies, is recruiting for a Co-op, Cell Therapy R&D Automation in the Cell Therapy Platform and Discovery Research Team for our site in Spring House, PA.
 

At the Janssen Pharmaceutical Companies of Johnson & Johnson, we are working to create a world without disease. Transforming lives by finding new and better ways to prevent, intercept, treat, and cure disease inspires us. We bring together the best minds and pursue the most promising science.
We are Janssen. We collaborate with the world for the health of everyone in it. Learn more at www.janssen.com and follow us @JanssenGlobal. Janssen Research & Development, LLC is part of the Janssen Pharmaceutical Companies.
 

The Cell Therapy Platform and Discovery Research Team within the Therapeutics Discovery (TD) division of Janssen R&D is engaged in the research and development of Chimeric Antigen Receptor (CAR)-directed autologous and allogeneic cell therapies. In this position, the Co-op student will learn about the exciting science Janssen is exploring in the CAR-T therapeutics research field, including viral vector technology development, T-cell transduction and expansion, cell engineering, immunophenotyping, and CAR-T cell QC and functional characterization. The Co-op student will also provide key support for enabling the research and development in these areas.
 

The position offers a phenomenal opportunity to engage in the discovery of next generation CAR-T technologies to address unmet medical needs. The Co-op student will:
•    Perform laboratory work supporting established biological assays, as well as developing and optimizing new assays. Responsibilities will include cell culture maintenance, reagent preparation, cell treatments, and applying a wide variety of analytical measurements including high-throughput flow cytometry, high-content confocal microscopy, kinetic cell killing assays, Meso Scale Discovery (MSD), and digital droplet PCR.
•    Troubleshoot technical difficulties in biological assays and data analysis procedures.
•    Develop and validate laboratory automation procedures for biological assays using machinery including the Biomek i7 liquid handling workstation, Viaflow-384 liquid handler, Formulatrix Mantis, BioTek plate washer, and Thermo Spinnaker robot arm.
•    Develop streamlined software templates for assay data processing, QC, and data visualization using programs such as Microsoft Excel VBA, GraphPad PRISM, and TIBCO Spotfire.
•    Perform laboratory operational support including studying experimental SOPs and equipment manuals, writing SOPs, ordering of reagents and supplies, testing new assay labware, registration of cell lines or chemical entities in internal databases, maintaining electronic data management resources, and coordinating equipment maintenance and new laboratory hardware evaluations with the technology vendors.
•    Carefully document all work in an electronic laboratory notebook meeting the Discovery Data Integrity standards at Janssen.