Senior Scientist, In Vivo Antibody Discovery

Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies is recruiting for a Senior Scientist, In Vivo Antibody Discovery located in Cambridge, MA.

At the Janssen Pharmaceutical Companies of Johnson & Johnson, what matters most is helping people live full and healthy lives. We focus on treating, curing and preventing some of the most devastating and complex diseases of our time. We pursue the most promising science, wherever it might be found.

Janssen Research & Development, LLC discovers and develops innovative medical solutions to address important unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, cardiovascular and metabolism, and pulmonary hypertension. Please visit http://www.janssenrnd.com for more information.

As a member of the Antibody Generation Group, this role will develop and implement methods to efficiently capture B-cell repertoires from immunized animals. The focus will be on next generation sequencing (NGS) approaches applied to sorted single B-cells and Hybridoma clones. Extensive experience with BCR cloning using RT-PCR, in-fusion cloning, multiplex NGS, and 10X Genomics are required. A strong understanding of B-cell isolation methods such as Hybridoma technology and primary B-cell sorting will also be important. This is a critical function in a multifaceted Biologics Discovery organization committed to bringing the next generation of biotherapeutic molecules to patients. We are looking for a motivated candidate with scientific and technical expertise who can collaborate across discovery areas to bring value to our portfolio of innovative drug concepts. Proficiency to lead within a highly coordinated, fast-paced environment will be a significant attribute. An additional knowledge base in the areas of oncology, immunology, infectious disease, or cardiovascular disease would be a plus. If this sounds like you, come join our team!