Senior Director, Vertical Platform Lead

content screening to advance pre-clinical research and development as well as manufacturing process optimization across therapeutic modalities.

Ginkgo is a partner driven company with over 100 programs running on the platform. We are seeking to enable drug-developers but have no designs to develop therapeutics ourselves. Within Ginkgo, the Mammalian Engineering team consists of a set of scientists and engineers with subject matter expertise across cell therapy, gene therapy, rna therapeutics, and biologics. This team is responsible for translating challenges our partners have into actionable R&D programs that leverage the broader Ginkgo platform's resources (aka the Foundry); and then manage and execute on those programs to deliver solutions on time and budget. Ginkgo has a number of public and confidential programs in RNA therapeutics, including developing next generation circular RNA and mRNA constructs with Pfizer, and triggering cell-type specific circularization with . We have also invested in RNA circularization technology through acquisition of Circularis. As a partner-driven platform company we are not focused on any particular therapeutic area and are generally interested in enabling the appropriate pharmacological characteristics for a partner's payload. These efforts blend with our teams' efforts in gene therapy and delivery technologies.

Reporting to the SVP, Foundry, the Vertical Lead will be responsible for building and managing our portfolio of vertical-specific therapeutic programs. Our verticals include RNA, Gene Therapy, Cell Therapy, Target Discovery and Biologics. Candidates for these roles will have had experiences both developing platform-specific approaches and driving preclinical and/or clinical programs with increasing leadership responsibilities throughout their career. The position requires a combination of deep technical understanding, general business acumen, project management skills, superior communication skills, and the ability to grow and lead scientific teams. Internal Title: Senior Director, RNA Therapeutics

Responsibilities:

• Leading and developing a team of scientists and engineers to deliver on programs across the portfolio
• Communicate performance to leadership and external customers
• Consult on and be aware of the Commercial vertical strategy and Commercial/URAD program roadmap within the vertical in alignment with leaders from Mammalian Engineering and Commercial.
• Responsible for the capability offering roadmap into the Foundry.
• Work in conjunction with Ginkgo's Commercial Team to directly interface with current and potential external partners to drive more programs on the platform. Provide vertical-specific input on the Mammalian portfolio strategy.
• Use those conversations to understand gaps and opportunities for Ginkgo to help vertical-specific developers. Formulate a strategy to address gaps or take advantage of opportunities through internal programs, licensing, acquisition, etc. that could drive significant value.
• Establish strong partnerships with Ginkgo's Foundry teams to develop a strategy to scale the numbers of programs Ginkgo can support- through standardization, institution of processes, etc.
• Define the strategic direction for Foundry pods within the vertical in alignment with leaders from Mammalian Engineering, translating our business needs into how we will execute.
• Participate in customer interactions in collaboration with Business Development and participate in scoping with the Platform Performance Leader (PPL)
• Accountable for the output of Foundry pods within the vertical.
• Assist with shaping Ginkgo's overall direction as a company and support its evolving needs, as necessary

Minimum Requirements:

• PhD in biology, biochemistry, bioengineering, computational biology or related field. Or equivalent experience with a Bachelor's degree
• 11+ years of research experience in biopharma R&D settings with at least 3 years industry experience in one of more verticals. Experiences both in platform development and program leadership
• Deep experience and technical leadership in one or more vertical-specific modalities
• Proven track record of leading and organizing successful teams and mentoring both managers and individual contributors
• Excellent project management skills, with the ability to oversee multiple projects simultaneously, meet deadlines, and collaborate with cross-functional teams
• Excellent communication and organization skills, with the ability to effectively convey project plans and complex technical information to a wide range of internal teams, executive leadership, and external partners

#LI-MB1

To learn more about Ginkgo, visit www.ginkgobioworks.com/press/ or check out some curated press below:

• What is it really like to take your company public via a SPAC? One Boston biotech shares its journey (Fortune)
• Ginkgo Bioworks resizes the definition of going big in biotech, raising $2.5B in a record SPAC deal that weighs in with a whopping $15B-plus valuation (Endpoints News)
• Ginkgo Bioworks CEO on scaling up Covid-19 testing: 'If we try, we can win' (CNBC)
• Ginkgo raises $70 million to ramp up COVID-19 testing for employers, universities (Boston Globe)
• Ginkgo Bioworks Redirects Its Biotech Platform to Coronavirus (Wall Street Journal)
• Ginkgo Bioworks Provides Support on Process Optimization to Moderna for COVID-19 Response (PRNewswire)
• The Life Factory: Synthetic Organisms From This $1.4 Billion Startup Will Revolutionize Manufacturing (Forbes)
• Synthetic Bio Pioneer Ginkgo Raises $290 Million in New Funding (Bloomberg)
• Ginkgo Bioworks raises $350 million fund for biotech spinouts (Reuters)
• Can This Company Convince You to Love GMOs? (The Atlantic)

We also feel that it's important to point out the obvious here - there's a serious lack of diversity in our industry, and that needs to change. Our goal is to help drive that change. Ginkgo is deeply committed to diversity, equity, and inclusion in all of its practices, especially when it comes to growing our team. Our culture promotes inclusion and embraces how rewarding it is to work with people from all walks of life.

We're developing a powerful biological engineering platform, so we must remain mindful of the many ways our technology can - and will - impact people around the world. We care about how our platform is used, and having a diverse team to build it gives us the best chance that it's something we'll be proud of as it continues to grow. Therefore, it's critical that we incorporate the diverse voices and visions of all those who play a role in the future of biology.

It is the policy of Ginkgo Bioworks to provide equal employment opportunities to all employees, employment applicants, and EOE disability/vet.

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