Senior Scientist - LC-MS Applications

inity enrichment, reagents, and their potential combinations.

The candidate to fill this position will have a strong support system to be able to accomplish important experiments and projects, such as aiding the development of novel chromatography columns, reagents as well as mass spectrometry methods involving large nucleic acid molecules, establishing, and transferring new quality control batch test procedures. As such, this scientist will help bring new technologies to the cell and gene therapy industry including charge detection mass spectrometry to characterize large intact molecule, and thereby help address problems that impact human health and society. This position offers an excellent opportunity to grow professionally and scientifically, and it gives a one-of-a-kind opportunity to work in an interdisciplinary environment with a diverse group of colleagues. This is a full time position, and the candidate will become an integral part of an interdisciplinary Research and Development team that supports hypothesis driven prototype evaluation, method development, and product commercialization.

Responsibilities

• Assist in hypothesis-driven experimentation to test and better understand reagents, LC column technologies and novel mass spectrometry methods along with their role in the analysis of gene therapy products especially large nucleic acids and viral vectors

• Implement test methods under general supervision and chip in to the preparation of reports and assisting with internal presentations to summarize scientific findings.

• Chip in to technical reports, QC & SOP procedures, literature and/or patent applications

• Help maintain laboratory instruments while crafting and maintaining records of test-related activities.

• Support products and customers during and after release

• Proactively learn about the biotechnology industry and emerging analysis methods through literature, conferences, and exchanges with customers and collaborators

Qualifications

A successful candidate should have:

• A PhD Degree in Analytical Chemistry with 0-3 years of focus on Bioanalytical chemistry involving LC-MS methodologies

• Experience in liquid chromatography including techniques involving large molecules, IP-RPLC and HILIC separations of oligonucleotides and nucleic acids

• Must have experience in mass spectrometry techniques including analysis of intact biomolecules and MS-based fragmentation techniques

• Experience in use of LC techniques for drug substance/product testing (desired)

• Strong chemical understanding of nucleic acids and other biomolecules

• Demonstration of impactful contributions to multiple scientific projects

• Experience with laboratory notebook documentation as well as reagent and buffer preparation

• Creativity and a keen curiosity about science

• Strengths in communication skills, collaborations, willing to give presentations, and writing #LI-CB1

Company Description

Waters Corporation (NYSE: WAT), the world's leading specialty measurement company, has pioneered chromatography, mass spectrometry and thermal analysis innovations serving the life, materials, and food sciences for over 60 years. With approximately 8,000 employees worldwide, Waters operates directly in 35 countries, including 15 manufacturing facilities, with products available in more than 100 countries. Our team focuses on creating business advantages for laboratory-dependent organizations to enable significant advancement in healthcare delivery, environmental management, food safety, and water quality.

Working at Waters enables our employees to unlock the potential of their careers. Our global team is driven by purpose. We strive to be better, learn and improve every day in everything we do. We're the problem solvers and innovators that aren't afraid to take risks to transform the world of human health and well-being. We're all in it together delivering benefit as one to provide the insights needed today in order to solve the challenges of tomorrow.

Diversity and inclusion are fundamental to our core values at Waters Corporation. It is our responsibility to actively implement programs and practices to drive inclusive behavior and increase diversity across the organization. We are united by diversity and thrive on it for the benefit of our employees, our products, our customers and our community. Waters is proud to be an equal opportunity workplace and is an affirmative action employer. We are committed to equal employment opportunity regardless of race, color, religion, sex, national origin, sexual orientation, age, marital status, disability, gender identity or protected Veteran status.

Key Words

Gene therapy, oligonucleotides, viral vectors, liquid chromatography, mass spectrometry, nucleic acid medicines, biotherapeutics